Clobenzorex (Asenlix, Dinintel, Finedal, Rexigen) is a stimulant drug of the phenethylamine and amphetamine chemical classes used as an appetite suppressant.asenlix 30mg,asenlix 30 mg,obeclox 30 mg,asenlix precio,obeclox lp
The drug is legally distributed in Mexico under the trade name Asenlix by Aventis.
Chemically, clobenzorex is an N-substituted amphetamine analog that is converted to d-amphetamine soon after ingestion. In commercial production, clobenzorex is supplied in 30 mg doses as the hydrochloride salt in green-tinted capsules.
The drug gained use as a prescription anorectic in the 1970s; however, adverse reactions were eventually observed, which led to the prohibition of clobenzorex in the United States and certain other countries.
In the United States, clobenzorex tablets (among other varieties of stimulants, such as amphetamine) have been used by athletes who ingest the drug to reduce fatigue, increase attention, and improve reaction times during athletic activities.
The green-tinted Asenlix capsules (generic forms can be seen as half light green, half dark green capsules marked “IFA”) are known as “greenies” among US baseball players, a slang term that in current use has expanded to generically refer to any amphetamine class stimulant.
Several metabolites of clobenzorex have been shown to be detected for a longer period of time than the parent. One of these, a hydroxy metabolite, was shown to be detected for an extended period of time.
In a study of urine samples provided following administration of a single 30-mg dose of this drug, 4-hydroxyclobenzorex could be detected for up to 91.5 h. More significantly, that study showed all samples that were positive for amphetamine also contained detectable amounts of 4-hydroxyclobenzorex.
This metabolite proved to be easily detected and was typically found at higher levels than amphetamine in urine samples positive for amphetamine long after clobenzorex itself could no longer be detected.asenlix 30mg,asenlix 30 mg,obeclox 30 mg,asenlix precio,obeclox lp
The present study analyzed samples from a controlled multidose administration (30 mg of clobenzorex daily for seven days) for the presence of 4-hydroxyclobenzorex.
The analytical procedure used acid hydrolysis followed by liquid-liquid extraction and gas chromatographic-mass spectrometric analysis with monitoring of ions at m/z 125, 330, and 364 for 4-hydroxyclobenzorex and its 3-Cl regioisomer, which was used as an internal standard.
Peak concentrations of 4-hydroxyclobenzorex ranged from 17,786 to 99,044 ng/mL.
Most importantly, this study also found that all samples that contained amphetamine at > or =500 ng/mL also contained detectable amounts of this hydroxy metabolite (LOD 10 ng/mL), making it a valuable tool in differentiating use of clobenzorex from illicit amphetamine use.asenlix 30mg,asenlix 30 mg,obeclox 30 mg,asenlix precio,obeclox lp