AM630

Description

Cannabinoids produce biochemical and pharmacological effects by interacting with the central cannabinoid (CB₁) and peripheral cannabinoid (CB₂) G protein-coupled receptors. AM630 is a selective CB₂ receptor antagonist that binds to CB₁ and CB₂ receptors with K_i values of 5.2 µM and 31.2 nM, respectively.¹ AM630 behaves as an inverse agonist at CB₂ receptors, attenuating the antinociceptive effects of a number of cannabinoids, and as a weak partial agonist at CB₁ receptors. ^1,2,3.

CAS Number:164178-33-0
Chemical and physical data
Formula C23H25IN2O3
Molar mass 504.360 g/mol